Benzopyrene is a polyaromatic hydrocarbon (PAH) formed most often during incomplete combustion of organic materials. It can be found in air, soil and water. Certain cooking methods like grilling forms PAHs and high fat and high protein foods form even more. It is also found in cigarette smoke.
According to a new study, researchers found that exposure to benzopyrene caused significant changes in mitochondria which drive energy production in cells. Most often there was a depletion of antioxidants and Kreb cycle enzymes, important for cell energy production, in the mitochondria. In addition, present was retarded growth rate in the liver and increased growth rate of other organs. The study demonstrated that the liver and lungs were most negatively effected by benzopyrene. Mitochondrial damages occurred in a dos-dependent manner!
Depletion of mitochondrial enzyme system in liver, lung, brain, stomach and kidney induced by benzo(a)pyrene. Environmental toxicology and pharmacology, Vol. 43 (4 March 2016), pp. 83-93 by Xiaoying Ji, Yongfei Li, Jianlong He, et al. http://www.citeulike.org/user/kimberlykramer2015/article/13978744
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