Omega 3 Fats are Nrf2 Activators - A Key Ingredient to a Healthy Diet!



It is believed the Western diet wholly or partially contributes to disease. "Sixty-five percent of Americans over 20 years of age are obese. 64 million people suffer from one or more type of cardiovascular disease." (Cordain) Many experts believe that one cause of the American diet's contribution to cardiovascular disease is the imbalance of fats. More specifically, a higher ratio of saturated fat and Omega 6 to omega 3 which are good fats.  Generally, the higher the consumption of omega-3 fats to other fats is correlated to a lower incidence of heart disease. (Dhalla) A recent study has shown that EPA omega 3 polyunsaturated fats protect against oxidative stress which contributes to heart disease. This is achieved by the EPA activating Nrf2 and Ho-1. (Lee)



For further reading:

     A Mediterranean Diet is Better Than Exercise and Can Halve the Risk of Heart Disease!
     The Mediterranean Diet : The Key to Preventing Disease and Life Extension?
     Natural Foods that Activate the Body's Antioxidant Response Against Cellular Stress


Origins and evolution of the Western diet: health implications for the 21st century The American Journal of Clinical Nutrition, Vol. 81, No. 2. (1 February 2005), pp. 341-354 by Loren Cordain, S. Boyd Eaton, Anthony Sebastian, et al. http://www.citeulike.org/user/kimberlykramer2015/article/13571703

Effects of eicosapentaenoic acid (EPA) on the cytoprotection via Nrf2-mediated heme oxygenase-1 in human endothelial cells. Journal of cardiovascular pharmacology (26 March 2015) by Seung Eun E. Lee, Gun-Dong D. Kim, Hana Yang, et al. http://www.citeulike.org/user/kimberlykramer2015/article/13571703

Role of oxidative stress in cardiovascular diseases. Journal of hypertension, Vol. 18, No. 6. (June 2000), pp. 655-673 by N. S. Dhalla, R. M. Temsah, T. Netticadan. http://www.citeulike.org/user/kimberlykramer2015/article/11296916