Loss Of Certain Gut Bacteria May Lead To Diabetes As We Age!

Losing one variety of gut bacteria may lead to type 2 diabetes as people age.

Old mice have less Akkermansia muciniphila bacteria than young mice do, researchers report November 14 in Science Translational Medicine. That loss triggers inflammation, which eventually leads cells to ignore signals from the hormone insulin. Such disregard for insulin’s message to take in glucose is known as insulin resistance and is a hallmark of type 2 diabetes. Read more...

Gut bacteria may guard against diabetes that comes with aging .Old mice lose one type of friendly microbe, triggering a hallmark of the disease . Tina Hesman Saey . Science News. November 19,2018.

Good Memory Depends On The Health Of Your Gut!

"Researchers have been conducting studies to determine how gut health and problems affect the body. Individuals who want to improve their memory may take into account taking better care of their gut." Read more...

Research Now Shows Gut Health Influences Good Memory. Melissa Scott Newswire. October 17, 2018

Gut Flora Changes In Alzheimer's May Lead to Endotoxemia!

"Alterations in gut microbiota in patients with Alzheimer's disease (AD) may be associated with increased bacterial endotoxins in the blood, a finding that may point the way to potential treatments, new research suggests." Read more...

Gut Microbiota Signature Altered in Alzheimer's Disease . Liam Davenport. Medscape.
October 11, 2018

Artificial Sweeteners Have Toxic Effects On The Gut Biome!

"A new study reports FDA approved artificial sweeteners and some sports supplements are toxic to digestive gut bacteria. Researchers say the consumption of artificial sweeteners can adversely affect gut microbial activity, causing a wide range of health issues from cancers to type-2 diabetes." Read more...

Artificial Sweeteners Have Toxic Effects on Gut Bacteria. Neuroscience News October 1, 2018.

The Harmful Effects of Low Carb Diets Illuminated!

"New research uses a "human gut simulator" to study the effects of two different diets on the composition of gut microbiota. Its findings illuminate the harms of having no carbs in the diet." Read more...

How a low-carb diet might impact gut health. Ana Sandoiu. Medical News Today. Tuesday 25 September 2018.

Gut Dysbiosis May Be A Factor in Chronic Fatigue Syndrome!

"Our results indicate dysbiosis of the gut microbiota in this disease and further suggest an increased incidence of microbial translocation, which may play a role in inflammatory symptoms in ME/CFS."

Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome. Microbiome, Vol. 4, No. 1. (23 June 2016) by Ludovic Giloteaux, Julia K. Goodrich, William A. Walters, et al.

Inflammation Starts in the Gut! Kick the High Fat Diet Habit!

In other posts, I have noted that one way to reduce the effects of environmental illnesses is to maintain a healthy diet that is low in fat. The main reasons for this is that high fat diets (HFD) 1) lead to dysbiosis. In other words, an unhealthy gut full of unhealthy gut bacteria and 2) HFD leads to obesity, more oxidative stress and inflammation that can lead to diabetes. (1-2)  Of course, since many patients with environmental illnesses already have higher oxidative stress. Anything that increases it is just going to make symptoms worse.

According to one recent study out of Chicago, researchers demonstrated that a HFD alters gut bacteria that makes fat gain easier. What they found is that "germ free" mice did not gain weight even when fed a HFD. On the other hand, mice with a "normal intestinal environment" and fed a HFD had an increase in bacteria that alter fat absorption and a decrease in bacteria linked to leanness. (3)

Browse The Catalog!

Related Post:
* Chemical in Broccoli May Help You Lose Weight!

*High-fat diet inhibits PGC-1α suppressive effect on NFκB signaling in hepatocytes. European journal of nutrition, Vol. 57, No. 5. (August 2018), pp. 1891-1900 by Wermerson Assunção A. Barroso, Vanessa Jacob J. Victorino, Isabela Casagrande C. Jeremias, et al.


1) Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, Vol. 28, No. 8. (August 2004), pp. 993-997 by M. Maachi, L. Piéroni, E. Bruckert, et al.

2. High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PloS one, Vol. 5, No. 8. (16 August 2010) by Shengli Ding, Michael M. Chi, Brooks P. Scull, et al.

3).Gut bacteria Could Be One Reason a Junk Food Diet Makes Us Put on Weight. Sam Downing. Coach. Nine. Com. Au. April 12, 2018. https://coach.nine.com.au/2018/04/12/10/07/gut-bacteria-high-fat-diet

Chronic Fatigue Syndrome Linked to Abnormal Gut Bacteria!

Abnormal levels of specific gut bacteria are related to chronic fatigue syndrome/myalgic encephalomyelitis, or ME/CFS, in patients with and without concurrent irritable bowel syndrome, or IBS, scientists have discovered. Read more...

Columbia University's Mailman School of Public Health. "Chronic fatigue syndrome linked to imbalanced microbiome: Scientists identify abnormal levels of specific gut bacteria in individuals with chronic fatigue syndrome, including those with and without co-morbid IBS." ScienceDaily. ScienceDaily, 26 April 2017. <www.sciencedaily.com/releases/2017/04/170426092351.htm>.

Probiotics May Improve Cognition in Patients with Fibromyalgia!

"A small pilot study found that eight weeks of treatment with probiotics — live microorganisms thought beneficial to the gut microbiota — significantly helped to improve some aspects of cognition in fibromyalgia patients, like impulsive choice and decision-making." Read more,,,

Note: Indiscriminate use of probiotics may lead to brain fog and bloating in fibromyalgia. Ask your doctor.
         Related Post: Indiscriminate Use of Probiotics Leads to Brain Fog and Bloating!



Treating Gut Microbiome with Probiotics Seen to Aid Cognitive Abilities in Pilot Study. July 25, 2018. https://fibromyalgianewstoday.com/2018/07/25/treating-gut-microbiome-with-probiotics-aids-cognitive-abilities-in-pilot-study-in-fibromyalgia-patients/

Berries Improve Gut Health and are Protective Against Neuroinflammation!

Experts believe that gut dysbiosis is a cause of environmental illness. Changes in the gut biome can be caused by antibiotic use, environmental insults from chemicals in food and water and high fat and high sugar diets. These changes lead to morphological changes in the wall of the intestines that allows for easier translocation of harmful bacteria. It is believed that translocation may be one significant cause of chronic fatigue syndrome. In addition, it is believed that dysbiosis may lead to neuroinflammation that is believed to be a major source of symptoms in chronic fatigue and fibromyalgia.

Numerous studies published in the recent past have shown that consumption of some fruits and herbs may improve gut health. Research has demonstrated that anthocyanins in berries may counteract dysbiosis. In addition, they also have anti-neuroinflammatory properties and allow for better communication between the gut and the brain. Lastly, they alter tryptophan metabolism increasing the neuroprotective metabolite kynurenic acid. (1) Incidentally, this pathway also produces the antioxidant 3-hydroxyanthranilic acid which inhibits inflammatory proteins by activating Nrf2. (2) 





1. Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins. Scientific reports, Vol. 8, No. 1. (27 July 2018) by Cláudia Marques, Iva Fernandes, Manuela Meireles, et al.

2. 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis, Vol. 187, No. 2. (August 2006), pp. 274-284 by Hyun-Ock O. Pae, Gi-Su S. Oh, Bok-Soo S. Lee, et al.

Gut microbiome able to ‘pass on’ disease, study suggests!

Gut bacteria implicated in the onset of obesity are able to survive outside the human body, raising suggestions this bacteria could be transferred from person to person, a study has suggested.

 

Gut microbiome able to ‘pass on’ disease, study suggests

By Will ChuWill Chu, 10-May-2016

Study: Gut Microbes May Be The Answer In Curing PTSD, Anxiety and Depression!

 

A team working in the field of warfighter performance suggests gut microbes may hold the key to curing or preventing post-traumatic stress disorder and mood disorders, such as anxiety and depression.

 PTSD could be prevented with gut microbes, study suggests. Catharine Paddock, PhD. Medical News Today. May 2, 2016. http://www.medicalnewstoday.com/articles/309600.php?utm_campaign=trueAnthem:+Trending+Content&utm_content=5727358a04d30158ba34ca85&utm_medium=trueAnthem&utm_source=facebook

Compound Found In Breast and Cows Milk Neccessary for Neonates Gut Microbiome!

 

Researchers have pinpointed the compound in breast milk that supplies the nourishment needed for the development of a neonates' gut microbiota, and they have shown that it can be obtained from cow's milk. The findings are published in the journal Applied and Environmental Microbiology.

 Gut microbiota development driven by specific enzyme in breast milk. Yvette Brazier. Medical News Today. April 16, 2016. http://www.medicalnewstoday.com/articles/309038.php

Gut Microbiome May Determine Effects of Malnutrition!

 

A new study has determined that the state of malnutrition, which is a condition that occurs across populations, may be influenced by the microbiome.  In a series of experiments, a researchers took samples from healthy children and transferred them to mice. These mice developed normally and did not show any signs of stunting which is a common condition caused from malnutrition. Alternatively, fecal samples from stunted children were transferred to germ free mice. Interestingly, these mice develop slow growth and stunting like the children the samples came from. The conclusion from this study is that the species of bacteria that make up the microbiome contribute to the effects of malnutrition. It is assumed that nutritious foods can be made with the healthy bacteria species and may one day help prevent the long-term effects of malnutrition.

 Persistent gut microbiota immaturity in malnourished Bangladeshi children. Nature, Vol. 510, No. 7505. (19 June 2014), pp. 417-421 by Sathish Subramanian, Sayeeda Huq, Tanya Yatsunenko, et al. http://www.citeulike.org/user/kimberlykramer2015/article/13939625

The right gut microbes help infants grow. Elizabeth Penissi. Science. February 18, 2016. http://www.sciencemag.org/news/2016/02/right-gut-microbes-help-infants-grow

Brain Chemical Made in the Gut Linked to Emotion and Depression!

Serotonin is probably best known as a brain chemical that affects emotions and behavior, an imbalance of which is thought to contribute to depression. Less well-known is that scientists estimate 90% of serotonin is made in the gut, and imbalances in this peripheral serotonin have been linked to diseases ranging from irritable bowel syndrome and cardiovascular disease, to osteoporosis.

Gut microbes important for serotonin production. Medical News Today. Catharine Paddock, Ph.D. April 21, 2015. http://www.medicalnewstoday.com/articles/292693.php

Kimchi Changes Balance of Bacteria in the Gut!

While I am not gonna jump on the bandwagon for this one, I thought I would note it because it shows how diet can influence gut health!

Consuming fermented kimchi, a source of lactobacilli, may alter the composition of bacterial populations in the gut and affect metabolic pathways for obese women, says a new study from Korea.

Can fermented kimchi alter the gut microbiota and influence metabolism? Nutraingredients-USA.com. Stephen DANIELLS, 30-Mar-2015http://www.nutraingredients-usa.com/Research/Can-fermented-kimchi-alter-the-gut-microbiota-and-influence-metabolism

How Do Probiotics Work? A New Research Reveal!

"The popular probiotic Lactobacillus rhamnosus GG may work by acting as 'a facilitator' that modifies and promotes the activity of other gut bacteria, say scientists."

How do probiotics work? Previously unknown 'facilitator' mechanism revealed NutraIngredients-USA.com (15 April 2015) by Niamh Michail+. http://www.nutraingredients-usa.com/Research/Probiotic-efficiency-revealed-by-previously-unknown-mechanism

Cheese is Good For Your Gut Microbiome!

In the study, researchers examined urine and fecal samples from 15 healthy men. Half of them ate cheese and milk in their diets, while the other half ate a control diet with butter, but no other dairy products. The researchers found that the participants who ate cheese had higher levels of butyrate in their fecal matter — a product of gut bacteria that is often associated with a reduction in cholesterol. As a result, the authors argue, high levels of cheese — despite its fatty content — could actually benefit you, and perhaps all saturated fats aren’t bad.

List Of Healthy Foods For Gut Bacteria Expands To Include Cheese. Medical Daily. Lecia Bushak. April 14, 2015. http://www.medicaldaily.com/list-healthy-foods-gut-bacteria-expands-include-cheese-329202