Hsieh found in a recent study that certain strains of Bifidobacteria reduce epithelial barrier disruption in the intestines. It is believed that intestinal barrier dysfunction leads to a number of diseases including inflammatory bowel disease. In this study, the author found that the actions on TNF-a were achieved by the whole Bifido cell. This shows, according to Hsieh, that bacterial metabolites must be produced that act to reduce TNF-a. He also found that different strains of Bifidobacteria achieve intestinal tight junction integrity better than others. This reinforces what I said in a previous post that more research is needed on the benefits of different strains of probiotics.
For Further Reading:
Inflammatory Bowel Disease, Helminths and High-fat Diets
Strengthening of the intestinal epithelial tight junction by Bifidobacterium bifidum Physiological Reports, Vol. 3, No. e12327. (16 March 2015) by Chen‐Yu Hsieh, Toshifumi Osaka, Eri Moriyama, et al
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