"Although bipolar disorder and depression are not found at this time in the NRF2 diseasome, it is becoming evident that they exhibit neuroinflammatory and degenerative pathophenotypes that at least in mouse models imply deregulation of NRF2".
Systems Medicine Approach to NRF2 in Chronic Diseases 375. NRF2 (Martin-de-Saavedra et al., 2013; Freitas et al., 2016; Yao et al., 2016).
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